Depending on the function you are in, make sure your SOAP service is running and that all publications are current, below is the list of all the publications: 

https://online-help.sageerpx3.com/erp/12/wp-static-content/whitepapers/en_US/negoce/adc/Content/How-to%20guides/Distribution/ADC/T4_ADC%20Web%20services.htm

You can also review the ADC logs and Syracuse W* node logs to determine the reason. 

Appreciate your response. Unfortunately, beyond my capabilities

Thanks