Sage Accpac Version 6.0

SQL 2008R2 on MS Windows Server

Server has 8 companies running. One of the Sage accpac companies has issues in posting batches from GL batch list window. Once you reboot server all postings will happen for 1st 5 minutes and after that it will freeze and no batches users can post from GL Batch list window. All other company databases do not have any issues yet. 

Activity monitor screenshot attached showing locks happening when Batch window freezes.

What could be causing it as bad network is ruled out as all clients connected to other companies are fine. Integrity check done nothing major reported. No new windows update in past week.