I have one coming up. I was hoping all I had to do was update the  SyncManager with the new path. 
I had the end user contact Beanworks who told them they would "push an update" as the upgrade time came closer.

We were told just to update the path in SyncManager as well which we did but still not connecting to the upgraded Sage. This is Sage 100 Premium v2022.2.

The resolution on this didn’t make a whole lot of sense. They changed the smartsync credentials from application level credentials to the credentials of a internal user and now Beanworks is pointing to the newly upgraded Sage.