Partners and customers are asked not to install Microsoft Security patch KB4516016 until further advised.
Have had a number of reported cases for across the installed base for Sage CRM for all supported versions.
This 3rd party article describes the underlying issue
https://stackoverflow.com/questions/58216515/error-asp-0115-a-trappable-error-has-occurred-after-microsoft-patch-cve-2019-1/58270956
Please contact your local support team for further information and advice.