Why is the 'Use Default Tax Code for Sales' tick box greyed out?

SOLVED

Hello,

On a couple of my customers, the tick box for 'Use Default Tax Code for Sales' is greyed out, when T22 is selected as the Default Tax code. Does anybody know what may be causing this? I've never seen it greyed out before and don't know what could be causing it (or what I might be missing).

(Sorry for the low-res screenshot)