Unable to open Sage since March 16th.

We are using 2011 version of Sage on Windows 10.   The system times out when we are trying to open the database with the message "Sage not responding".   It looked like there was a Windows update around the same time so we backed it but the same message appears.  Before I do anything else I thought I would check with people who know more than I do.   Thank-you everyone for any help that can be given.  Victoria