Cannot open database because the database engine reported an error

I recently changed my data drive (E:) with two 3TB drives using Storage Spaces in Win 10 as one drive with replication (similar to RAID 1). I chose GPT as the format. Now I get a error saying Simply cannot open the database because the database engine reported an error. The error log reports the following:

160524 11:32:53  InnoDB: Operating system error number 87 in a file operation.
InnoDB: Some operating system error numbers are described at
InnoDB: dev.mysql.com/.../operating-system-error-codes.html
InnoDB: File name .\ib_logfile0
InnoDB: File operation call: 'aio read'.
InnoDB: Cannot continue operation.

I can transfer the Simply data files to my Drive C (SSD), and Simply opens the database ok. I have made sure the properties of the folder on my E drive allow all access to all users, so that should not be the problem.

Amy suggestions?