Sage 300 statement designer not working with non-local admin account


Could you please help me with this. I have Sage 300 and O365 32-bits run on the same server. and trying to generate the report from "Statement Designer" section. 

When I login with local admin account to the server and run Sage app (normal sage credentials) and run the report it works, but when I login with normal domain account to the server the statement designer as soon as Excel opens up it throws some micro erros and misbehave generally.  

Is there something like in the background to the local admin privilege? 

Thank you very much,